| Identification | Back Directory | [Name]
18,19-Dinorpregn-4-en-20-yn-3-one-2,2,4,6,6,10-d6, 13-ethyl-17-hydroxy-, (17α)- | [CAS]
2376035-98-0 | [Synonyms]
18,19-Dinorpregn-4-en-20-yn-3-one-2,2,4,6,6,10-d6, 13-ethyl-17-hydroxy-, (17α)- | [Molecular Formula]
C21H28O2 | [MOL File]
2376035-98-0.mol | [Molecular Weight]
312.45 |
| Hazard Information | Back Directory | [Description]
Levonorgestrel-d6 is intended for use as an internal standard for the quantification of levonorgestrel by GC- or LC-MS. Levonorgestrel is a synthetic progestin and the biologically active component of norgestrel .1 In vivo, levonorgestrel (60 μg/day) suppresses estrus and pregnancy in female cats.2 Post-coital insertion of subdermal levonorgestrel (5 mg pellet) implants prevents uterine implantation of embryos in mice.3 Formulations containing levonorgestrel have been used as contraceptives. | [Uses]
Norgestrel-d6 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Norgestrel-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
1. Jones, R.C., Singer, A.C., and Edgren, R.A. The biological activities of norgestrel and its enantiomers Int. J. Fertil. 24(1),39-43(1979).
2. Baldwin, C.J., Peter, A.T., Bosu, W.T., et al. The contraceptive effects of levonorgestrel in the domestic cat Lab. Anim. Sci. 44(3),261-269(1994).
3. Shirley, B., Bundren, J.C., and McKinney, S. Levonorgestrel as a postcoital contraceptive Contraception 52(2),277-281(1995). |
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guoyungurui
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