| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-PEG3-NH2 dihydrochloride (VH032-PEG3-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology[1] | [storage]
Store at -20°C | [References]
[1] Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513. DOI:10.1021/acs.jmedchem.6b01912
[2] Salami J, et al. Waste disposal-An attractive strategy for cancer therapy. Science. 2017;355(6330):1163-1167. DOI:10.1126/science.aam7340 |
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R&D Systems, Inc
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18003437475 18003437475 |
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www.rndsystems.com |
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Enzo Biochem Inc
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Enzo Biochem Inc. 13797054060 |
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www.enzo.com |
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