| Identification | Back Directory | [Name]
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[[1-[1-[(1-methylcyclobutyl)methyl]-4-piperidinyl]-1H-pyrazol-4-yl]methyl]amino]- | [CAS]
2377849-57-3 | [Synonyms]
E3 ligase Ligand 22
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[[1-[1-[(1-methylcyclobutyl)methyl]-4-piperidinyl]-1H-pyrazol-4-yl]methyl]amino]- | [Molecular Formula]
C28H34N6O4 | [MOL File]
2377849-57-3.mol | [Molecular Weight]
518.61 |
| Hazard Information | Back Directory | [Uses]
E3 ligase Ligand 22 (compound 139) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway[1]. | [IC 50]
Cereblon | [References]
[1] Gesine Kerstin VEITS, et al. Cereblon binders for the degradation of ikaros. WO2019191112A1. |
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