| Identification | Back Directory | [Name]
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH | [CAS]
2378261-80-2 | [Synonyms]
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH | [Molecular Formula]
C23H43NO9 | [MDL Number]
MFCD32690105 | [MOL File]
2378261-80-2.mol | [Molecular Weight]
477.59 |
| Chemical Properties | Back Directory | [Boiling point ]
573.2±50.0 °C(Predicted) | [density ]
1.15±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C, stored under nitrogen | [solubility ]
Soluble in DMSO | [form ]
Liquid | [pka]
14.77±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523)[1]. | [Biological Activity]
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 [1]. | [IC 50]
PEGs | [References]
[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2. |
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