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μ opioid receptor agonist 3 (compound 20) is a potent μ opioid receptor (μOR) agonist with an EC50 of 0.87 nM. μ opioid receptor agonist 3 has the potential for pain and neuropsychiatric indications research[1]. | [IC 50]
μ Opioid Receptor/MOR: 0.82 nM (EC50) | [References]
[1] Alok Nerurkar, et al. Novel series of tunable μOR modulators with enhanced brain penetration for the treatment of opioid use disorder, pain and neuropsychiatric indications. Bioorg Med Chem Lett. 2023 Aug 15:92:129405. DOI:10.1016/j.bmcl.2023.129405 |
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