| Identification | Back Directory | [Name]
1H-Pyrazole-3-methanol, 1-[2-[[[2-(4-amino-1-piperidinyl)-8-(1-methylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]-3-chlorophenyl]-α,α-dimethyl- | [CAS]
2378710-04-2 | [Synonyms]
CDK7-IN-6
1H-Pyrazole-3-methanol, 1-[2-[[[2-(4-amino-1-piperidinyl)-8-(1-methylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]-3-chlorophenyl]-α,α-dimethyl- | [Molecular Formula]
C26H34ClN9O | [MOL File]
2378710-04-2.mol | [Molecular Weight]
524.07 |
| Hazard Information | Back Directory | [Uses]
CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer[1]. | [IC 50]
CDK7: ≤100 nM (IC50) | [References]
[1] Kiyean NAM, et al.Preparation of pyrazolotriazine and/or pyrazolopyrimidine derivatives as selective inhibitor of cyclin dependent kinase. WO2019197549 A1. |
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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