| Identification | Back Directory | [Name]
Benzenesulfonamide, N-[[[4-(4-bromophenyl)-2-thiazolyl]amino]carbonyl]-4-methyl- | [CAS]
2379335-06-3 | [Synonyms]
Anticancer agent 34
Benzenesulfonamide, N-[[[4-(4-bromophenyl)-2-thiazolyl]amino]carbonyl]-4-methyl- | [Molecular Formula]
C17H14BrN3O3S2 | [MOL File]
2379335-06-3.mol | [Molecular Weight]
452.35 |
| Hazard Information | Back Directory | [Uses]
Anticancer agent 34 (compound 9), a sulfonylurea derivative, is a potent antimicrobial and anticancer agent. Anticancer agent 34 inhibits the microbial growth of B. mycoides, E. coli, and C. albicans with a MIC between 0.156 and 0.039 mg/ml. Anticancer agent 34 inhibits A549, PC3 cell growth with IC50s of 8.4 μg/ml, 7.8 μg/ml, respectively[1]. | [References]
[1] Farid M. Sroor, et al. Anticancer and antimicrobial activities of new thiazolyl-urea derivatives: gene expression, DNA damage, DNA fragmentation and SAR studies. Medicinal Chemistry Research volume 31, pages400–415 (2022). |
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