| Identification | Back Directory | [Name]
N-[2-Cyclohexyl-4-(1-methylethyl)phenyl]-5-(tetrahydro-2H-pyran-2-yl)-2-furanmethanamine | [CAS]
2379989-52-1 | [Synonyms]
N-[2-Cyclohexyl-4-(1-methylethyl)phenyl]-5-(tetrahydro-2H-pyran-2-yl)-2-furanmethanamine | [Molecular Formula]
C25H35NO2 | [MOL File]
2379989-52-1.mol | [Molecular Weight]
381.55 |
| Chemical Properties | Back Directory | [Boiling point ]
501.3±50.0 °C(Predicted) | [density ]
1.072±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble to 50 mM in DMSO and to 10 mM in ethanol | [form ]
powder | [pka]
4.85±0.50(Predicted) | [color ]
white to beige | [InChI]
1S/C25H35NO2/c1-18(2)20-11-13-23(22(16-20)19-8-4-3-5-9-19)26-17-21-12-14-25(28-21)24-10-6-7-15-27-24/h11-14,16,18-19,24,26H,3-10,15,17H2,1-2H3 | [InChIKey]
GYTVCHRGONLGMD-UHFFFAOYSA-N | [SMILES]
CC(C)C(C=C1C2CCCCC2)=CC=C1NCC3=CC=C(C4OCCCC4)O3 |
| Hazard Information | Back Directory | [Uses]
CITFA is a GPER agonist. CITFA can promote neurite growth of hippocampal neurons in rat embryo (E18)[1]. | [Biological Activity]
CITFA is a potent GPER agonist (EC50 = 38.7 nM). It significantly increases axonal and dendritic growth in rat embryonic (E18) hippocampal neurons. | [storage]
Store at -20°C | [References]
[1] DeLeon C, et al. Novel GPER Agonist, CITFA, Increases Neurite Growth in Rat Embryonic (E18) Hippocampal Neurons. ACS Chem Neurosci. 2022 Apr 20;13(8):1119-1128. DOI:10.1021/acschemneuro.1c00811 |
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