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2382961-86-4

2382961-86-4 Structure

2382961-86-4 Structure
IdentificationBack Directory
[Name]

1H-Benzimidazole-2-propanol, 5,7-dichloro-6-(4,4-difluoro-1-piperidinyl)-γ-[4-(ethylsulfonyl)phenyl]-, (γR)-
[CAS]

2382961-86-4
[Synonyms]

SHR168442
1H-Benzimidazole-2-propanol, 5,7-dichloro-6-(4,4-difluoro-1-piperidinyl)-γ-[4-(ethylsulfonyl)phenyl]-, (γR)-
[Molecular Formula]

C23H25Cl2F2N3O3S
[MOL File]

2382961-86-4.mol
[Molecular Weight]

532.43
Chemical PropertiesBack Directory
[Boiling point ]

777.0±60.0 °C(Predicted)
[density ]

1.50±0.1 g/cm3(Predicted)
[pka]

9.55±0.30(Predicted)
Hazard InformationBack Directory
[Uses]

SHR168442 is a modulator of retinoid-related orphan receptor gamma (RORγ) with an IC50 value of 0.035 μM.
[IC 50]

ROR-γ
[References]

[1] Yan Y, et al. Benzimidazole derivatives as modulators of retinoid-related orphan receptor gamma (ror?) and pharmaceutical uses thereof. WO2019213470 A1.
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