Identification | Back Directory | [Name]
1H-Benzimidazole-2-propanol, 5,7-dichloro-6-(4,4-difluoro-1-piperidinyl)-γ-[4-(ethylsulfonyl)phenyl]-, (γR)- | [CAS]
2382961-86-4 | [Synonyms]
SHR168442 1H-Benzimidazole-2-propanol, 5,7-dichloro-6-(4,4-difluoro-1-piperidinyl)-γ-[4-(ethylsulfonyl)phenyl]-, (γR)- | [Molecular Formula]
C23H25Cl2F2N3O3S | [MOL File]
2382961-86-4.mol | [Molecular Weight]
532.43 |
Hazard Information | Back Directory | [Uses]
SHR168442 is a modulator of retinoid-related orphan receptor gamma (RORγ) with an IC50 value of 0.035 μM. | [IC 50]
ROR-γ | [References]
[1] Yan Y, et al. Benzimidazole derivatives as modulators of retinoid-related orphan receptor gamma (ror?) and pharmaceutical uses thereof. WO2019213470 A1. |
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