| Identification | Back Directory | [Name]
Cyclophosphamide Impurity 20 | [CAS]
2387771-96-0 | [Synonyms]
Cyclophosphamide Impurity 20
2-((2-Chloroethyl)(2-ethoxyethyl)amino)-1,3,2-oxazaphosphinane 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N-(2-chloroethyl)-N-(2-ethoxyethyl)tetrahydro-, 2-oxide
N-?(2-?Chloroethyl)?-?N-?(2-?ethoxyethyl)?tetrahydro-2H-?1,?3,?2-?Oxazaphosphorin-?2-?amine 2-?Oxide
Cyclophosphamide Impurity 20Q: What is
Cyclophosphamide Impurity 20 Q: What is the CAS Number of
Cyclophosphamide Impurity 20 | [Molecular Formula]
C9H20ClN2O3P | [MOL File]
2387771-96-0.mol | [Molecular Weight]
270.69 |
| Hazard Information | Back Directory | [Uses]
N-?(2-?Chloroethyl)?-?N-?(2-?ethoxyethyl)?tetrahydro-2H-?1,?3,?2-?Oxazaphosphorin-?2-?amine 2-?Oxide is an impurity of Cyclophosphamide (C988580), a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen. |
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