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23915-73-3

23915-73-3 Structure

23915-73-3 Structure
IdentificationBack Directory
[Name]

Trebenzomine
[CAS]

23915-73-3
[Synonyms]

Trebenzomine
N,N,2-Trimethyl-3-chromanamine
2H-1-Benzopyran-3-amine, 3,4-dihydro-N,N,2-trimethyl-
3,4-Dihydro-3-(dimethylamino)-2-methyl-2H-1-benzopyran
[Molecular Formula]

C12H17NO
[MDL Number]

MFCD00865473
[MOL File]

23915-73-3.mol
[Molecular Weight]

191.27
Chemical PropertiesBack Directory
[Boiling point ]

276.7±29.0 °C(Predicted)
[density ]

1.04±0.1 g/cm3(Predicted)
[pka]

8.82±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Trebenzomine (CI-686 free base) is a centrally acting psychotropic compound. Trebenzomine has both neuroleptic and stimulant activity. Trebenzomine potentiates Methamphetamine-induced self-stimulation. Trebenzomine reduces septal hyperirritability, suppression of conditioned avoidance behavior, blocks Apomorphine (HY-12723)-induced emesis in dogs[1].
[References]

[1] Georgotas A, et al. A double-blind comparison of trebenzomine and thioridazine in the treatment of schizophrenia. Psychopharmacology (Berl). 1981;73(3):292-4. DOI:10.1007/BF00422420
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