| Hazard Information | Back Directory | [Description]
Bilaid A1 is a tetrapeptide agonist of the μ-opioid receptor (Ki = 750 nM in HEK293 cell membranes expressing the human receptor) and a derivative of bilaid A .1 It inhibits forskolin-induced cAMP accumulation by 47% in HEK293 cells expressing the human μ-opioid receptor when used at a concentration of 10 μM. | [Uses]
Bilaid A1e (Compound 1e) is a tetrapeptide agonist of the μ-opioid receptor (Ki = 750 nM). Bilaid A1e can be isolated from an Australian estuarine isolate of Penicillium sp. Bilaid A1e can be used for pain research[1]. | [IC 50]
μ Opioid Receptor/MOR: 750 nM (Ki) | [References]
1. Dekan, Z., Sianati, S., Yousuf, A., et al. A tetrapeptide class of biased analgesics from an Australian fungus targets the μ-opioid receptor Proc. Natl. Acad. Sci. USA 116(44),22353-22358(2019). |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
ChemeGen 中国
|
| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
| Company Name: |
|
| Tel: |
4008-099-669 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList112975/0.htm |
|