| Chemical Properties | Back Directory | [Melting point ]
137-138 °C | [Boiling point ]
511.4±60.0 °C(predicted) | [density ]
1.20±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
4.38±0.10(predicted) |
| Hazard Information | Back Directory | [Uses]
ALDH1A1-IN-4 (compound A1) is a potent inhibitor of aldehyde dehydrogenase (ALDH) A1, with IC50 value of 0.32 μM. ALDH1A1-IN-4 plays an important role in cancer research[1]. | [IC 50]
ALDH1A1: 0.32 μM (IC50) | [References]
[1] Gera Narendra, et al. Scaffold hopping based designing of selective ALDH1A1 inhibitors to overcome cyclophosphamide resistance: synthesis and biological evaluation. RSC Med Chem. 2023 Nov 30;15(1):309-321. DOI:10.1039/d3md00543g |
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