| Identification | Back Directory | [Name]
Benzamide, N,N-dimethyl-4-[2-[4-(4-methyl-1-piperazinyl)phenyl]-5H-pyrrolo[2,3-b]pyrazin-7-yl]- | [CAS]
2403600-07-5 | [Synonyms]
HPK1-IN-17
Benzamide, N,N-dimethyl-4-[2-[4-(4-methyl-1-piperazinyl)phenyl]-5H-pyrrolo[2,3-b]pyrazin-7-yl]- | [Molecular Formula]
C26H28N6O | [MOL File]
2403600-07-5.mol | [Molecular Weight]
440.54 |
| Hazard Information | Back Directory | [Uses]
HPK1-IN-17 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-17 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2019238067A1, compound 73)[1]. | [References]
[1] Jing Li, et al. Pyrrolo [2, 3-b] pyridines or pyrrolo [2, 3-b] pyrazines as hpk1 inhibitor and the use thereof. Patent WO2019238067A1. |
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