2408268-38-0

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2408268-38-0 Structure

Identification	Back Directory
[Name] 1,2-Benzenediol, 4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)methyl]-
[CAS] 2408268-38-0
[Synonyms] TLR7 agonist 23 1,2-Benzenediol, 4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)methyl]-
[Molecular Formula] C21H22N4O2
[MOL File] 2408268-38-0.mol
[Molecular Weight] 362.43

Chemical Properties	Back Directory
[Boiling point ] 683.5±55.0 °C(predicted)
[density ] 1.35±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 9.64±0.10(predicted)

Hazard Information	Back Directory
[Uses] TLR7 agonist 23 (compound 12b) is a potent Toll Like Receptor-7 (TLR7) agonist with a EC50 of 0.15 uM. TLR7 agonist 23 can be used in the study of immunological diseases[1].
[References] [1] Kumar K, et al. Design and Synthesis of Polyphenolic Imidazo [4, 5-c] quinoline Derivatives to Modulate Toll Like Receptor-7 Agonistic Activity and Adjuvanticity[J]. ACS Pharmacology & Translational Science, 2024.

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