| Identification | Back Directory | [Name]
PF-07265807 | [CAS]
2412356-57-9 | [Synonyms]
PF-07265807
TAM&Met-IN-1
5-Pyrimidinecarboxamide, N-[3-fluoro-4-[[3-[[(1R)-2-hydroxy-1-methylethyl]amino]-1H-pyrazolo[3,4-b]pyridin-4-yl]oxy]phenyl]-3-(4-fluorophenyl)-1,2,3,4-tetrahydro-1-(1-methylethyl)-2,4-dioxo- | [Molecular Formula]
C29H27F2N7O5 | [MOL File]
2412356-57-9.mol | [Molecular Weight]
591.57 |
| Hazard Information | Back Directory | [Uses]
PF-07265807 is a potent TAM and c-Met kinase inhibitor with IC50 values of 6.1 nM, 13.2 nM and 21.6 nM for AXL, MER and TYRO3, respectively. PF-07265807 can be used for researching anticancer[1]. | [IC 50]
Axl; Tyro3; Mer | [References]
[1] Ronald Jay Hinklin, et al. PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES. WO2020047184A1 (example 1). |
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