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BAY-593 (hydrochloride) is an orally active GGTase-I inhibitor. BAY-593 (hydrochloride) can block YAP1/TAZ signaling in animals and has antitumor activity[1]. | [References]
[1] Graham K, et al. Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol. 2024 Mar 19:S2451-9456(24)00087-4. DOI:10.1016/j.chembiol.2024.02.013 |
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R&D Systems, Inc
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18003437475 18003437475 |
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www.rndsystems.com |
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