| Identification | Back Directory | [Name]
Hexanamide, 5-methyl-3-[[(2S)-3-methyl-1-oxo-2-[[[4-[(1E)-2-phenylethenyl]phenyl]sulfonyl]amino]butyl]amino]-2-oxo-, (3S)- | [CAS]
2413962-65-7 | [Synonyms]
Hexanamide, 5-methyl-3-[[(2S)-3-methyl-1-oxo-2-[[[4-[(1E)-2-phenylethenyl]phenyl]sulfonyl]amino]butyl]amino]-2-oxo-, (3S)- | [Molecular Formula]
C26H33N3O5S | [MOL File]
2413962-65-7.mol | [Molecular Weight]
499.62 |
| Hazard Information | Back Directory | [Uses]
Calpain Inhibitor-2 (compound 5) is a peptide inhibitor of μ-calpain (Ki=9 nM). Calpain Inhibitor-2 exhibits antiproliferative activity against melanoma cell lines (A-375 and B-16F1) and PC-3 prostate cancer cells in vitro[1]. | [References]
[1] Donkor IO,et al. Synthesis and antiproliferative activity of sulfonamide-based peptidomimetic calpain inhibitors. Bioorg Med Chem. 2020 May 1;28(9):115433. DOI:10.1016/j.bmc.2020.115433 |
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