| Identification | Back Directory | [Name]
5H-Quinindoline, 3-methoxy-5-methyl-11-(3-methylbutyl)- | [CAS]
2414491-13-5 | [Synonyms]
Anticancer agent 75
5H-Quinindoline, 3-methoxy-5-methyl-11-(3-methylbutyl)- | [Molecular Formula]
C22H24N2O | [MOL File]
2414491-13-5.mol | [Molecular Weight]
332.45 |
| Hazard Information | Back Directory | [Uses]
Anticancer agent 75 is a potent anticancer agent. Anticancer agent 75 shows cytotoxicity and selectivity in cancer cell lines. Anticancer agent 75 shows cytotoxicity to normal human kidney cell lines is at least 35 times lower than that of the Doxorubicin standard. Anticancer agent 75 shows good activity of antiplasmodial[1]. | [IC 50]
Plasmodium; Topoisomerase II | [References]
[1] Bhornrawin Akkachairin, et al. Synthesis of Neocryptolepines and Carbocycle-Fused Quinolines and Evaluation of Their Anticancer and Antiplasmodial Activities. Journal Pre-proofs. 2020, 98: 103732. DOI:10.1016/j.bioorg.2020.103732 |
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