| Identification | Back Directory | [Name]
4-Piperidinecarboxylic acid, 1-[4-(aminosulfonyl)benzoyl]-, 2-[[[(4-methoxyphenyl)methyl]amino]carbonyl]hydrazide | [CAS]
2414601-79-7 | [Synonyms]
hCAXII-IN-4
4-Piperidinecarboxylic acid, 1-[4-(aminosulfonyl)benzoyl]-, 2-[[[(4-methoxyphenyl)methyl]amino]carbonyl]hydrazide | [Molecular Formula]
C22H27N5O6S | [MOL File]
2414601-79-7.mol | [Molecular Weight]
489.54 |
| Hazard Information | Back Directory | [Uses]
hCAXII-IN-4 (compound 5j) is a potent and selective CA XII inhibitor with an Ki value of 6.4 nM for human CA XII[1]. | [References]
[1] Moi D, et al. Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors. Bioorg Chem. 2020 May;98:103728. DOI:10.1016/j.bioorg.2020.103728 |
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