| Identification | Back Directory | [Name]
4-Quinazolinamine, N-2-benzothiazolyl-6-bromo-2-(3-pyridinyl)- | [CAS]
2414635-72-4 | [Synonyms]
EGFR-IN-63
4-Quinazolinamine, N-2-benzothiazolyl-6-bromo-2-(3-pyridinyl)- | [Molecular Formula]
C20H12BrN5S | [MOL File]
2414635-72-4.mol | [Molecular Weight]
434.31 |
| Hazard Information | Back Directory | [Uses]
EGFR-IN-63 is an EGFR inhibition (IC50: 0.096 μM) and it has anticancer activity in MCF-7 cells (IC50: 2.49 μM). | [References]
[1] Heba Abdelrasheed Allam, et al, Design and Synthesis of some new 2,4,6-trisubstituted quinazoline EGFR inhibitors as targeted anticancer agents, Bioorg Chem. 2020 May;98:103726 DOI:10.1016/j.bioorg.2020.103726 |
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