2415674-94-9

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2415674-94-9 Structure

Identification	Back Directory
[Name] Azido-dPEG???-OH
[CAS] 2415674-94-9
[Synonyms] Azido-dPEG24-OH N3-PEG24-OH/71-Azido-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-tricosaoxahenheptacontan-1-ol
[Molecular Formula] C48H97N3O24
[MOL File] 2415674-94-9.mol
[Molecular Weight] 1100.3

Hazard Information	Back Directory
[Uses] Azido-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG24-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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