| Identification | Back Directory | [Name]
Butanamide, 4-(4-bromophenoxy)-N-(2-oxo-3-oxazolidinyl)- | [CAS]
2415981-79-0 | [Synonyms]
YXL-13
Butanamide, 4-(4-bromophenoxy)-N-(2-oxo-3-oxazolidinyl)- | [Molecular Formula]
C13H15BrN2O4 | [MOL File]
2415981-79-0.mol | [Molecular Weight]
343.17 |
| Hazard Information | Back Directory | [Uses]
YXL-13 is a potent Pseudomonas aeruginosa (PAO1) inhibitor with an IC50 value of 3.686 μM. YXL-13 can inhibit virulence factors and biofilm formation of PAO1. YXL-13 reduces the pathogenicity and agent resistance of PAO1 by inhibition of the quorum sensing (QS) system. YXL-13 can be used for researching anti-bacteria[1]. | [References]
[1] Jiang K, Yan X, Yu J, et al. Design, synthesis, and biological evaluation of 3-amino-2-oxazolidinone derivatives as potent quorum-sensing inhibitors of Pseudomonas aeruginosa PAO1. Eur J Med Chem. 2020;194:112252. DOI:10.1016/j.ejmech.2020.112252 |
|
|