| Identification | Back Directory | [Name]
3-Azetidinecarboxaldehyde, 1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]- | [CAS]
2416132-70-0 | [Synonyms]
Thalidomide-azetidine-CHO
1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)azetidine-3-carbaldehyde
1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]azetidine-3-carbaldehyde
3-Azetidinecarboxaldehyde, 1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]- | [Molecular Formula]
C17H15N3O5 | [MOL File]
2416132-70-0.mol | [Molecular Weight]
341.32 |
| Hazard Information | Back Directory | [Uses]
Thalidomide-azetidine-CHO is a synthesized Ligands for E3 Ligase that incorporates the Thalidomide (HY-14658) based cereblon ligand used in PROTAC technology[1]. | [IC 50]
Cereblon | [References]
[1] Wuhan Humanwell Innovative Drug Research and Development Center Limited Company; Humanwell Healthcare (Group) Co., Ltd. Preparation of imidazopyridine compounds as IRAK4 degraders. China, CN117777126 A 2024-03-29 |
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