Identification | Back Directory | [Name]
1H-[1,4]Oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione, 12-[(6S)-9,10-difluoro-6,11-dihydro-2-methylbenzo[e]-1-benzothieno[7,6-b]thiepin-6-yl]-3,4,12,12a-tetrahydro-7-hydroxy-, (12aR)- | [CAS]
2416258-53-0 | [Synonyms]
Cap-dependent endonuclease-IN-5 1H-[1,4]Oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione, 12-[(6S)-9,10-difluoro-6,11-dihydro-2-methylbenzo[e]-1-benzothieno[7,6-b]thiepin-6-yl]-3,4,12,12a-tetrahydro-7-hydroxy-, (12aR)- | [Molecular Formula]
C27H21F2N3O4S2 | [MOL File]
2416258-53-0.mol | [Molecular Weight]
553.6 |
Hazard Information | Back Directory | [Uses]
Cap-dependent endonuclease-IN-5 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-5 inhibits influenza virus well, and/or has lower cytotoxicity, better in vivo pharmacokinetic properties and in vivo pharmacodynamic properties (extracted from patent WO2020078401A1, compound 13-1)[1]. | [References]
[1] Huichao LUO, et al. Influenza virus replication inhibitor and uses thereof. Patent WO2020078401A1. |
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