| Identification | Back Directory | [Name]
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- | [CAS]
2416312-06-4 | [Synonyms]
QW24
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- | [Molecular Formula]
C27H28N2O4 | [MOL File]
2416312-06-4.mol | [Molecular Weight]
444.52 |
| Hazard Information | Back Directory | [Uses]
QW24 exerts potent anti-tumor activity by down-regulating BMI-1 and is used as an effective therapeutic agent for clinical colorectal cancer research. | [References]
[1] Wang J, et al. A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer. J Exp Clin Cancer Res. 2019 Oct 22;38(1):422. DOI:10.1186/s13046-019-1392-8 |
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