| Identification | Back Directory | [Name]
NSC 135130 | [CAS]
24164-06-5 | [Synonyms]
NSC 135130
L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-, methyl ester
(S)-methyl 2-((tert-butoxycarbonyl)(methyl)amino)-3-methylbutanoate
Methyl (S)-2-((tert-butoxycarbonyl)(methyl)amino)-3-methylbutanoate | [Molecular Formula]
C12H23NO4 | [MOL File]
24164-06-5.mol | [Molecular Weight]
245.32 |
| Chemical Properties | Back Directory | [Boiling point ]
293.5±19.0 °C(Predicted) | [density ]
1.015±0.06 g/cm3(Predicted) | [form ]
Liquid | [pka]
-1.67±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates[1]. | [References]
[1] Malkov AV, Vranková K, Cerny M, Kocovsky P. On the selective N-methylation of BOC-protected amino acids. J Org Chem. 2009 Nov 6;74(21):8425-7. DOI:10.1021/jo9016293 |
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