ChemicalBook--->CAS DataBase List--->24164-06-5

24164-06-5

24164-06-5 Structure

24164-06-5 Structure
IdentificationBack Directory
[Name]

NSC 135130
[CAS]

24164-06-5
[Synonyms]

NSC 135130
L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-, methyl ester
(S)-methyl 2-((tert-butoxycarbonyl)(methyl)amino)-3-methylbutanoate
Methyl (S)-2-((tert-butoxycarbonyl)(methyl)amino)-3-methylbutanoate
[Molecular Formula]

C12H23NO4
[MOL File]

24164-06-5.mol
[Molecular Weight]

245.32
Chemical PropertiesBack Directory
[Boiling point ]

293.5±19.0 °C(Predicted)
[density ]

1.015±0.06 g/cm3(Predicted)
[form ]

Liquid
[pka]

-1.67±0.70(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates[1].
[References]

[1] Malkov AV, Vranková K, Cerny M, Kocovsky P. On the selective N-methylation of BOC-protected amino acids. J Org Chem. 2009 Nov 6;74(21):8425-7. DOI:10.1021/jo9016293
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