| Identification | Back Directory | [Name]
1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)- | [CAS]
2416873-72-6 | [Synonyms]
1,3-Cyclopentanediamine, N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)-, (1R,3R)- | [Molecular Formula]
C14H21N5 | [MOL File]
2416873-72-6.mol | [Molecular Weight]
259.35 |
| Chemical Properties | Back Directory | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
(Powder or Lyophilized powder or film or oil) | [pka]
10.40±0.40(Predicted) | [color ]
colorless to brown-yellow |
| Hazard Information | Back Directory | [Biological Activity]
KI-ARv-03 is a cell penetrantpotent and selective inhibitor of CDK9 th at th at reduces AR-driven transcription and proliferation in prostate cancer cells. KI-ARv-03 modulates AR and AR-V7-dependent transcription in 22Rv1 cells. It exhibits potent anti-tumor activity in castration-resistant prostate cancer (CRPC) models. |
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|