| Identification | Back Directory | [Name]
Benzenesulfonamide, 4-[4-[[3-[(1E)-3-(3-methoxyphenyl)-3-oxo-1-propen-1-yl]-1H-indol-1-yl]methyl]-1H-1,2,3-triazol-1-yl]- | [CAS]
2417232-26-7 | [Synonyms]
hCA I-IN-1
Benzenesulfonamide, 4-[4-[[3-[(1E)-3-(3-methoxyphenyl)-3-oxo-1-propen-1-yl]-1H-indol-1-yl]methyl]-1H-1,2,3-triazol-1-yl]- | [Molecular Formula]
C27H23N5O4S | [MOL File]
2417232-26-7.mol | [Molecular Weight]
513.57 |
| Hazard Information | Back Directory | [Uses]
hCA I-IN-1 (Compound 6q) is a human carbonic anhydrase I (hCA I) inhibitor with Ki values of 38.3, 716.4, 940.1 and 192.8 nM against hCA I, hCA II, hCAIX and hCAXII, respectively[1]. | [References]
[1] Singh P, et al. Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids. Bioorg Chem. 2020 Jun;99:103839. DOI:10.1016/j.bioorg.2020.103839 |
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