| Identification | Back Directory | [Name]
3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)- | [CAS]
2417373-18-1 | [Synonyms]
3-Pyridinecarboxamide, N-[3-(aminosulfonyl)phenyl]-2-(4,4-difluoro-1-piperidinyl)-5-(trifluoromethyl)- | [Molecular Formula]
C18H17F5N4O3S | [MOL File]
2417373-18-1.mol | [Molecular Weight]
464.41 |
| Hazard Information | Back Directory | [Uses]
Nav1.8-IN-14 (compound 20) is a potent and selective Nav1.8 inhibitor. Nav1.8-IN-14 can be used in the study of pain-related diseases[1]. | [References]
[1] Breslin MJ, et al. 2-Aminopyridines as Potent and Selective Nav1.8 Inhibitors Exhibiting Efficacy in a Nonhuman Primate Pain Model. ACS Med Chem Lett. 2024 May 24;15(6):917-923. DOI:10.1021/acsmedchemlett.4c00103 |
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