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2418022-85-0

2418022-85-0 Structure

2418022-85-0 Structure
IdentificationBack Directory
[Name]

Benzenesulfonyl fluoride, 3-[[[5-chloro-4-[[1,2-dihydro-8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-6-quinolinyl]amino]-2-pyrimidinyl]amino]methyl]-
[CAS]

2418022-85-0
[Synonyms]

Benzenesulfonyl fluoride, 3-[[[5-chloro-4-[[1,2-dihydro-8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-6-quinolinyl]amino]-2-pyrimidinyl]amino]methyl]-
[Molecular Formula]

C25H24ClFN6O6S
[MOL File]

2418022-85-0.mol
[Molecular Weight]

591.01
Chemical PropertiesBack Directory
[density ]

1.54±0.1 g/cm3(Predicted)
[pka]

14.73±0.46(Predicted)
Hazard InformationBack Directory
[Description]

TMX-2164 is a BCL6 inhibitor.
[Uses]

TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC50 value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells[1].
[References]

[1] Teng M, et, al. Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface. ACS Med Chem Lett. 2020 Apr 3;11(6):1269-1273. DOI:10.1021/acsmedchemlett.0c00111
2418022-85-0 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Tags:2418022-85-0 Related Product Information

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