| Identification | Back Directory | [Name]
Benzenesulfonamide, 4-[[(1,3-benzodioxol-5-ylamino)thioxomethyl]amino]-N-2-thiazolyl- | [CAS]
2418549-30-9 | [Synonyms]
EGFR-IN-54
Benzenesulfonamide, 4-[[(1,3-benzodioxol-5-ylamino)thioxomethyl]amino]-N-2-thiazolyl- | [Molecular Formula]
C17H14N4O4S3 | [MOL File]
2418549-30-9.mol | [Molecular Weight]
434.51 |
| Hazard Information | Back Directory | [Uses]
EGFR-IN-54 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 1.623 μM. EGFR-IN-54 shows cytotoxic activity against cancer cell lines[1]. | [IC 50]
EGFR: 1.623 μM (IC50) | [References]
[1] Abbas SY, et al. Synthesis and anticancer activity of thiourea derivatives bearing a benzodioxole moiety with EGFR inhibitory activity, apoptosis assay and molecular docking study. Eur J Med Chem. 2020 Jul 15;198:112363. DOI:10.1016/j.ejmech.2020.112363 |
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