| Hazard Information | Back Directory | [Uses]
anti-TNBC agent-2 (3j) an anti-Triple negative breast cancer (TNBC) purine derivative. anti-TNBC agent-2 induces MDA-MB-231 cells apoptosis, and inhibits its migration and angiogenesis. anti-TNBC agent-2 inhibits tumor growth and metastasis and reduces the expression of Ki67 and CD31 protein in TNBC xenograft models. anti-TNBC agent-2 can be used for Triple negative breast cancer (TNBC) research[1]. | [References]
[1] Zhang Q, et al. Synthesis and mechanism of action of new purine derivatives against triple negative breast cancer. Eur J Med Chem. 2023 Sep 7;261:115797. DOI:10.1016/j.ejmech.2023.115797 |
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