| Identification | Back Directory | [Name]
Benzo[h]quinoline-2,5,6(1H)-trione, 3,4-dihydro-4-(3-hydroxy-4-methoxyphenyl)- | [CAS]
2432823-48-6 | [Synonyms]
Antitumor agent-57
Benzo[h]quinoline-2,5,6(1H)-trione, 3,4-dihydro-4-(3-hydroxy-4-methoxyphenyl)- | [Molecular Formula]
C20H15NO5 | [MOL File]
2432823-48-6.mol | [Molecular Weight]
349.34 |
| Hazard Information | Back Directory | [Uses]
Antitumor agent-57 (Compound 3o) is an NQO1-directed antitumor agent. Antitumor agent-57 inhibits tumor cell growth, triggers ROS generation and induces cell apoptosis[1]. | [References]
[1] Wu LQ, et al. Design, synthesis, and biological evaluation of 4-substituted-3,4-dihydrobenzo[h]quinoline-2,5,6(1H)-triones as NQO1-directed antitumor agents. Eur J Med Chem. 2020 Jul 15;198:112396. DOI:10.1016/j.ejmech.2020.112396 |
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