| Identification | Back Directory | [Name]
2-Pyridineacetamide, N-[5-[4-[6-[[3-[1-[(4-methylphenyl)methyl]-1H-1,2,3-triazol-4-yl]-1-oxopropyl]amino]-3-pyridazinyl]butyl]-1,3,4-thiadiazol-2-yl]- | [CAS]
2435781-94-3 | [Synonyms]
GLS1 Inhibitor-3
2-Pyridineacetamide, N-[5-[4-[6-[[3-[1-[(4-methylphenyl)methyl]-1H-1,2,3-triazol-4-yl]-1-oxopropyl]amino]-3-pyridazinyl]butyl]-1,3,4-thiadiazol-2-yl]- | [Molecular Formula]
C30H32N10O2S | [MOL File]
2435781-94-3.mol | [Molecular Weight]
596.71 |
| Hazard Information | Back Directory | [Uses]
GLS1 Inhibitor-3 (compound C147) is a potent GLS1 inhibitor with an IC50 of 27.98 nM. GLS1 Inhibitor-3 shows antiproliferative activity[1]. | [References]
[1] Xu X, et al. Discovery of novel glutaminase 1 allosteric inhibitor with 4-piperidinamine linker and aromatic heterocycles. Eur J Med Chem. 2022 Jun 5;236:114337. DOI:10.1016/j.ejmech.2022.114337 |
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