Identification | Back Directory | [Name]
4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-methoxy-2-benzothiazolyl)-, (4S)- | [CAS]
24404-90-8 | [Synonyms]
6′-Methoxyluciferin 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-methoxy-2-benzothiazolyl)-, (4S)- | [Molecular Formula]
C12H10N2O3S2 | [MOL File]
24404-90-8.mol | [Molecular Weight]
294.35 |
Chemical Properties | Back Directory | [Boiling point ]
543.2±60.0 °C(Predicted) | [density ]
1?+-.0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.27±0.20(Predicted) | [color ]
Off-white to light yellow |
Hazard Information | Back Directory | [Uses]
D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 μM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site[1]. | [References]
[1] Giuseppe Meroni, et al. D-Luciferin, derivatives and analogues: synthesis and in vitro/in vivo luciferase-catalyzed bioluminescent activity. Volume 2009, Issue 1, Reviews and Accounts, pp. 265-288 |
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Abcam Limited
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021-2070050 400921018 |
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www.abcam.cn |
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