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IdentificationBack Directory
[CAS]

244277-89-2
[Molecular Formula]

C24H36N2O2
[Molecular Weight]

384.55
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

<50.06mg/ml in DMSO; <25.03mg/ml in ethanol
Hazard InformationBack Directory
[Uses]

J 104129 is a mAChR M3 antagonist.
[in vivo]

J-104129 (10 mg/kg; p.o.; single) shows durable bronchodilatory action lasting over 10 h in rats[1][2].
J-104129 (p.o.) antagonizes ACh-induced bronchoconstriction with an ED50 value of 0.58 mg/kg in rats[1].

Animal Model:Male Sprague-Dawley rats[1][2].
Dosage:10 mg/kg
Administration:Oral administration; single.
Result:Exhibited bronchodilatory activity.
[storage]

Store at -20°C
244277-89-2 suppliers list
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Telephone: 18930552037
Website: www.chemicalbook.com/showsupplierproductslist13285/0_en.htm
Company Name: Energy Chemical  
Telephone: 400-0056266
Website: www.energy-chemical.com
Company Name: MedBioPharmaceutical Technology Inc  
Telephone: 021-69568360 18916172912
Website: http://www.med-bio.cn/
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.  
Telephone: +86-057181025280; +8617767106207
Website: https://www.molcore.com/
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