| Identification | Back Directory | [Name]
Benzenesulfonamide, N-[[5-[(acetyloxy)methyl]-1H-1,2,3-triazol-4-yl]methyl]-4-iodo- | [CAS]
2452118-54-4 | [Synonyms]
VIM-2-IN-1
Benzenesulfonamide, N-[[5-[(acetyloxy)methyl]-1H-1,2,3-triazol-4-yl]methyl]-4-iodo- | [Molecular Formula]
C12H13IN4O4S | [MOL File]
2452118-54-4.mol | [Molecular Weight]
436.23 |
| Hazard Information | Back Directory | [Uses]
VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 μM, 48 μM and 231 μM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively[1]. | [References]
[1] Zeeshan Muhammad, et al. Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases. Bioorg Med Chem. 2020 Aug 1;28(15):115598. DOI:10.1016/j.bmc.2020.115598 |
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