| Identification | Back Directory | [Name]
Cyclopentanol, 2-[[2-amino-7-(1H-pyrazol-3-yl)-4-quinazolinyl]amino]-, (1S,2R)- | [CAS]
2454017-83-3 | [Synonyms]
NLRP3 antagonist 1
Cyclopentanol, 2-[[2-amino-7-(1H-pyrazol-3-yl)-4-quinazolinyl]amino]-, (1S,2R)- | [Molecular Formula]
C16H18N6O | [MOL File]
2454017-83-3.mol | [Molecular Weight]
310.35 |
| Chemical Properties | Back Directory | [Boiling point ]
698.7±65.0 °C(Predicted) | [density ]
1.475±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
12.00±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
NLRP3 antagonist 1 is a potent antagonist of NLRP3. NLRP3 is mainly expressed in macrophages and neutrophils and is involved in the body's intrinsic immunity against pathogenic infections and stress injury. NLRP3 antagonist 1 has the potential for the research of cancer disease (extracted from patent WO2021114691A1, compound 3)[1]. | [References]
[1] Zejin You, et al. Nitrogen-containing and cyclic compounds, their preparation methods and uses. Patent WO2021114691A1. |
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