| Identification | Back Directory | [Name]
Dihydrocubebin | [CAS]
24563-03-9 | [Synonyms]
Dihydrocubebin
Dihydrocubebin, rel-
(2R,3R)-2,3-Bis(1,3-benzodioxole-5-ylmethyl)-1,4-butanediol
(2R,3R)-2,3-Bis[(1,3-benzodioxole-5-yl)methyl]-1,4-butanediol
1,4-Butanediol, 2,3-bis(1,3-benzodioxol-5-ylmethyl)-, (2R,3R)-
[2R,3R,(-)]-2,3-Bis(1,3-benzodioxole-5-ylmethyl)-1,4-butanediol | [Molecular Formula]
C20H22O6 | [MOL File]
24563-03-9.mol | [Molecular Weight]
358.39 |
| Hazard Information | Back Directory | [Uses]
Dihydrocubebin is a compound isolated from Piper cubeba as potent and selective inhibitors against cytochrome P450 3A4 (CYP3A4)[1]. | [Definition]
ChEBI: Dihydrocubebin is a glycol that is butane-1,4-diol substituted at the 2- and 3-positions by (1,3-benzodioxol-5-yl)methyl groups (the R,R-configuration). It is a lignan, a member of butanediols, a glycol and a member of benzodioxoles. | [References]
[1] Usia T, et al. Metabolite-cytochrome P450 complex formation by methylenedioxyphenyl lignans of Piper cubeba: mechanism-based inhibition. Life Sci. 2005;76(20):2381-2391. DOI:10.1016/j.lfs.2004.12.005 |
|
|