| Identification | Back Directory | [Name]
Benzeneacetamide, N-[4-[[(phenylamino)carbonyl]amino]phenyl]- | [CAS]
2456315-41-4 | [Synonyms]
VEGFR-2-IN-19
Benzeneacetamide, N-[4-[[(phenylamino)carbonyl]amino]phenyl]- | [Molecular Formula]
C21H19N3O2 | [MOL File]
2456315-41-4.mol | [Molecular Weight]
345.39 |
| Hazard Information | Back Directory | [Uses]
VEGFR-2-IN-19 (Compound 15b) is a potent VEGFR2 inhibitor. VEGFR-2-IN-19 induces cell apoptosis and increases intracellular reactive oxygen species level. VEGFR-2-IN-19 can be used as an anticancer agent[1]. | [IC 50]
VEGFR2 | [References]
[1] Azimian F, et al. Synthesis and biological evaluation of diaryl urea derivatives designed as potential anticarcinoma agents using de novo structure-based lead optimization approach. Eur J Med Chem. 2020 Sep 1;201:112461. DOI:10.1016/j.ejmech.2020.112461 |
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