| Identification | Back Directory | [Name]
Mecbotamab | [CAS]
2460400-28-4 | [Synonyms]
Mecbotamab
Research Grade Mecbotamab
Research Grade Mecbotamab (DHD89504) |
| Hazard Information | Back Directory | [Uses]
Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011)[1][2]. | [IC 50]
Axl | [References]
[1] Shen G G, et al. Population pharmacokinetic and exposure-response safety analyses of mecbotamab vedotin (BA3011) in patients with advanced solid tumors[J]. 2023.
[2] Mecbotamab. IMGT/mAb-DB. |
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Cell Sciences
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www.cellsciences.com |
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