| Identification | Back Directory | [Name]
(R)-1-[(S)-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENYL]-ETHYLDI-TERT-BUTYLPHOSPHINE | [CAS]
246231-79-8 | [Synonyms]
JOSIPHOS SL-J011-1
JOSIPHOS SL-J011-2
(R)-(-)-1-[(S)-2-Di-t-butylphosphino)ferrocenyl]ethyldi-(4-CF3-phenyl)phosphine
(R)-1-{(S)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}-ethyldi-tert.-
(R)-(-)-1-[(S)-2-Di-tert-butylphosphino)ferrocenyl]ethyldi-(4-trifluoromethylphenyl)phosph
(R)-1-[(S)-2-Di-(4-trifluoromethylphenylphos-phino)ferrocenyl]-ethyl-di-tert-butylphosphine
(R)-(-)-1-[(S)-2-(BIS(4-TRIFLUOROMETHYLPHENYL)PHOSPHINO)FERROCENYL]ETHYL-DI-T-BUTYLPHOSPHINE
(R)-1-[(S)-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENYL]-ETHYLDI-TERT-BUTYLPHOSPHINE
(S)-1-[(R)-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENYL]-ETHYLDI-TERT-BUTYLPHOSPHINE
(R,R)-1-[1-(DI-TERT-BUTYLPHOSPHINO)ETHYL]-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENE
(S,S)-1-[1-(DI-TERT-BUTYLPHOSPHINO)ETHYL]-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENE
(R)-(-)-1-[(S)-(2-DI-TERT-BUTYLPHOSPHINO)FERROCENYL]ETHYLDI-(4-TRIFLUOROMETHYLPHENYL)PHOSPHINE
(R)-(-)-1-{(SP)-2-[Bis(4-trifluoromethylphenyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine
(R)-1-{(SP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine >=97%
(R)-(-)-1-{(S)-2-(Bis(4-trifluoromethylphenyl)phosphino]ferrocenyl}ethyl-di-t-butylphosphine,min.97%
(R)-(-)-1-{(S)-2-[Bis(4-trifluoromethylphenyl) phosphino]ferrocenyl} ethyl-di-t-butylphosphine, min. 97%
(r,r)-1-[1-(di-tert-butylphosphino)ethyl]-2-{bis[4-(trifluoromethyl)phenyl]phosphino}ferrocene (acc to cas)
(2R)-1-[(1R)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-[bis[4-(trifluoromethyl)phenyl]phosphino]ferrocene
(R)-(-)-1-{(S)-2-(Bis(4-trifluoromethylphenyl)phosphino]ferrocenyl}ethyl-
di-t-butylphosphine, min. 97%
(R)-1-[(S)-2-Di-(4-trifluoroMethylphenylphos-phino)ferrocenyl]-ethyl-di-tert-butylphosphine, Manufactured by Solvias AG | [Molecular Formula]
C34H38F6FeP2 10* | [MDL Number]
MFCD04038736 | [MOL File]
246231-79-8.mol | [Molecular Weight]
678.45 |
| Chemical Properties | Back Directory | [Appearance]
Orange powder | [alpha ]
-352° ±10° (c 0.5, CHCl3) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
Powder | [color ]
orange |
| Questions And Answer | Back Directory | [Reaction]
- Ferrocenylphosphine ligands of the type cpFecp(PR2)(*CH(CH3)PR'2) are a class of asymmetric ligands developed at Solvias in Basel, Switzerland. Ligands of this type are currently used industrially in the stereoselective synthesis of commercial products. A unique feature of these bidentate ligands is the presence of a fixed phosphine moiety and a stereogenic, functionalized side chain, which can be easily modified to accommodate electronic and steric requirements. Based on a versatile synthetic procedure starting with optically active ferrocenes of the type cpFecp(PR2)(*CH(CH3)X) [X = OAc or NR2], a variety of donor atoms can be introduced into the side chain. These ferrocene based phosphine ligands have wide application in the stereoselective hydrogenation of substituted acetamidoacrylates, enol acetates, β-ketoesters and simple alkenes.
- Useful as a ligand in Pd-catalyzed C-N bond-forming reactions.
- Pd-catalyzed enantioselective alkylative desymmetrization of meso-succinic anhydrides.
- Asymmetric hydrogenation of ketones and phosphinylketimines.
- Michael addition of Grignard reagents to α,α-unsaturated esters and thioesters.
- Boration of α,α-unsaturated esters and nitriles.
- Reaction of aryl halides with ammonia.
- Cu-catalyzed reduction of activated C=C bonds with PMHS.
- Regio- and enantioselective hydroboration of vinyl arenes.
- Rh-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes.
- 1,2-Migrations in Pd-catalyzed Negishi couplings with JosiPhos ligands.
- Catalyst for the homodimerization of ketoketenes.
- Ligand for the Rh catalyzed synthesis of lactones.
- Ligand for the Cu-catalyzed synthesis of syn and anti γ-amino alcohols.
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