| Identification | Back Directory | [Name]
7beta-Methoxyrosmanol | [CAS]
24703-38-6 | [Synonyms]
7β-methoxyrosmanol
7-O-Methylepirosmanol
7beta-Methoxyrosmanol
2H-10,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-9-methoxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9R,10S,10aS)- | [Molecular Formula]
C21H28O5 | [MOL File]
24703-38-6.mol | [Molecular Weight]
360.44 |
| Hazard Information | Back Directory | [Uses]
(-)-7-Methoxyrosmanol ((-)-7-O-Methoxyrosmanol) is a phenolic diterpene with antioxidant activity. (-)-7-Methoxyrosmanol is produced from carnosic acid by oxidation and cyclization, can induce cell cycle arrest and apoptosis in neuroblastoma cells[1][2][3]. | [References]
[1] Tabata K, et al. Phenolic diterpenes derived from Hyptis incana induce apoptosis and G(2)/M arrest of neuroblastoma cells. Anticancer Res. 2012 Nov;32(11):4781-9. PMID:23155243
[2] Jiang Z Y, et al. Perovskatone A: a novel C23 terpenoid from Perovskia atriplicifolia[J]. Tetrahedron letters, 2013, 54(29): 3886-3888.
[3] Richheimer S L, et al. Antioxidant activity of lipid-soluble phenolic diterpenes from rosemary[J]. Journal of the American Oil Chemists’ Society, 1996, 73(4): 507-514. |
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