ChemicalBook--->CAS DataBase List--->24730-10-7

24730-10-7

24730-10-7 Structure

24730-10-7 Structure
IdentificationBack Directory
[Name]

DIHYDROERGOCRISTINE MESYLATE
[CAS]

24730-10-7
[Synonyms]

C13168
DHEC (mesylate)
dihydroergocristinmesilat
DIHYDROERGOCRISTINE MESYLATE
Dihydroergocristine mesilate CRS
DIHYDROERGOCRISTINE METHANESULFONATE
Dihydroergocristine mesilate (D1945000)
DIHYDROERGOCRYSTINE METHANESULFONATE SALT
dihydroergocristine methanesulfonate salt
Dihydroergotamine Mesilate Impurity E as Mesilate
9,10-dihydro-ergocristinmonomethanesulfonate(salt)
Dihydroergotamine Mesilate EP Impurity E as Mesilate
(5’-alpha,10-alpha)-nylmethyl)monomethanesulfonate(salt)
DIHYDROERGOCRISTINE METHANESULFONATE ERG OT ALKALOID, VASOC
ergotamane-3’,6’,18-trione,9,10-dihydro-12’-hydroxy-2’-(1-methylethyl)-5’-(phe
(5,10a)-9,10-Dihydro-12hydroxy-2(1-methylethyl)-5(phenylmethyl)-ergotamane-3618-trionemesylate]
5'alpha-benzyl-9,10alpha-dihydro-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione monomethanesulphonate
(5'α,10α)-9,10-Dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-ergotaman-3',6',18-trionemesylate
(5'A,10A)-9,10-DIHYDRO-12'-HYDROXY-2'-(1-METHYLETHYL)-5'-(PHENYLMETHYL)-ERGOTAMAN-3',6',18-TRIONE MESYLATE
(5'alpha, 10alpha)-9,10-Dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-ergotaman-3',6',18-trione mesylate
Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy- 2'-(1-methylethyl)-5'-(phenylmethyl)-, (5'α,10α)-, monomethanesulfonate (salt)
[EINECS(EC#)]

246-434-6
[Molecular Formula]

C36H45N5O8S
[MDL Number]

MFCD00153792
[MOL File]

24730-10-7.mol
[Molecular Weight]

707.84
Chemical PropertiesBack Directory
[Appearance]

White or almost white, fine crystalline powder.
[Melting point ]

210 °C
[storage temp. ]

Store at RT
[solubility ]

H2O: 10 mg/mL
[form ]

neat
[color ]

White to off-white
Hazard InformationBack Directory
[Chemical Properties]

White or almost white, fine crystalline powder.
[Uses]

4,10-Dihydroergocristine Methanesulfonate is an nontoxic and well tolerated drug that exerts agonistic and antagonistic activity on dopaminergic and adrenergic receptors. 4,10-Dihydroergocristine Meth anesulfonate is known to exhibit protective properties to the brain against metabolic effects of ischemia by acting at a cellular level.
[Uses]

Alpha receptor blocking
[Definition]

ChEBI: The methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. It is also a component of ergoloid mesylat (codergocrine mesilate), a mixture of ergot alkaloid derivatives that is used as a vasodilator and has shown mild benefits in the treatment of vascular dementia.
[Biological Activity]

5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors.
[storage]

Room temperature
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H303
[Precautionary statements ]

P270-P301+P312-P403-P501c
[RIDADR ]

UN 1544 6.1/PG 2
[WGK Germany ]

2
[RTECS ]

KE7600000
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[HS Code ]

29396900
Spectrum DetailBack Directory
[Spectrum Detail]

DIHYDROERGOCRISTINE MESYLATE(24730-10-7)1HNMR
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