| Identification | Back Directory | [Name]
2H-Furo[2,3-h]-1-benzopyran-2,9(8H)-dione, 8-[(4-hydroxy-3-nitrophenyl)methylene]-4-methyl-, (8Z)- | [CAS]
2473524-63-7 | [Synonyms]
Neuraminidase-IN-5
2H-Furo[2,3-h]-1-benzopyran-2,9(8H)-dione, 8-[(4-hydroxy-3-nitrophenyl)methylene]-4-methyl-, (8Z)- | [Molecular Formula]
C19H11NO7 | [MOL File]
2473524-63-7.mol | [Molecular Weight]
365.29 |
| Hazard Information | Back Directory | [Uses]
Neuraminidase-IN-5 (Compound 5b) is a potent inhibitor of neuraminidase with an IC50 of 0.02 μM. Neuraminidase (NA) is a promising target for development of anti-influenza agents. Neuraminidase-IN-5 is a dihydrofurocoumarin derivative compound[1]. | [References]
[1] Zhong ZJ, et al. Design, synthesis and biological evaluation of dihydrofurocoumarin derivatives as potent neuraminidase inhibitors. Bioorg Med Chem Lett. 2021;37:127839. DOI:10.1016/j.bmcl.2021.127839 |
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