| Identification | Back Directory | [Name]
DSPE-COOH | [CAS]
248253-94-3 | [Synonyms]
DSPE-COOH
DSPE-succinic acid
8,10,14-Trioxa-5-aza-9-phosphadotriacontanoic acid, 9-hydroxy-4,15-dioxo-12-[(1-oxooctadecyl)oxy]-, 9-oxide, (12R)- | [Molecular Formula]
C45H86NO11P | [MOL File]
248253-94-3.mol | [Molecular Weight]
848.14 |
| Hazard Information | Back Directory | [Uses]
DSPE-succinic acid is a phophalipid capped with a carboxylic acid moiety. The carboxylic acid moiety is reactive with amine to from a stable amide linkage. DSPE-succinic acid can be used to prepare nanoparticles or liposomes for agent nanocarrier to deliver therapeutics[1]. | [References]
[1] iviere K, et al. Antitumor effect of folate-targeted liposomal doxorubicin in KB tumor-bearing mice after intravenous administration. J Drug Target. 2011 Jan;19(1):14-24. DOI:10.3109/10611861003733953 |
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