| Identification | Back Directory | [Name]
CC15009 | [CAS]
2482713-67-5 | [Synonyms]
CC15009
Morpholine, 4-[3-[2,6-dichloro-4-[3-(4-pyridinyl)-1H-1,2,4-triazol-5-yl]phenoxy]propyl]- | [Molecular Formula]
C20H21Cl2N5O2 | [MOL File]
2482713-67-5.mol | [Molecular Weight]
434.32 |
| Chemical Properties | Back Directory | [Boiling point ]
671.9±65.0 °C(predicted) | [density ]
1.342±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
7.67±0.10(predicted) |
| Hazard Information | Back Directory | [Uses]
CC15009 is a xanthine oxidoreductase (XOR) inhibitor, with an IC50 value of 0.237 nM. CC15009 can inhibit the oxidative subtype of XOR, thereby reducing the production of the byproduct ROS and exhibiting antioxidant activity. CC15009 has demonstrated a good dose-dependent uric acid-lowering effect in two different mouse models of hyperuricemia induced by XOR substrates[1]. | [References]
[1] Li X, et al. Identification of a novel xanthine oxidoreductase inhibitor for hyperuricemia treatment with high efficacy and safety profile. Biomed Pharmacother. 2024 Sep;178:117223. DOI:10.1016/j.biopha.2024.117223 |
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