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248282-07-7

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248282-07-7 Structure

248282-07-7 Structure
IdentificationBack Directory
[Name]

Laquinimod
[CAS]

248282-07-7
[Synonyms]

TV 5600
Laquinimod
LaquinimodSodium
ABR 215062 SodiuM
LaquiniMod SodiuM Salt
5-Chloro-N-ethyl-1,2-dihydro-4-hydroxy-1-Methyl-2-oxo-N-phenyl-3-quinolinecarboxaMide SodiuM Salt
N-Ethyl-N-phenyl-1,2-dihydro-4- hydroxy-5-chloro-1-Methyl-2-oxoquinoline-3-carboxaMide SodiuM Salt
[Molecular Formula]

C19H18ClN2NaO3
[MDL Number]

MFCD25976425
[MOL File]

248282-07-7.mol
[Molecular Weight]

380.8
Hazard InformationBack Directory
[Uses]

Laquinimod is an oral drug used for treatment of lupus arthritis.
[in vivo]

Laquinimod sodium treatment inhibits donor myelin-specific T cells from transferring EAE to naive recipient mice. In vivo laquinimod treatment alters subpopulations of myeloid antigen presenting cells (APC) that include a decrease in CD11c+CD11b+CD4+dendritic cells (DC) and an elevation of CD11bhiGr1hi monocytes[1].

[IC 50]

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