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2483830-13-1

2483830-13-1 Structure

2483830-13-1 Structure
IdentificationBack Directory
[Name]

15N2, 98%)
[CAS]

2483830-13-1
[Synonyms]

Hazard InformationBack Directory
[Uses]

Thymine-13C5,15N2 (5-Methyluacil-13C5,15N2) is 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[1].
[References]

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45(11 Pt 1):5553-6. PMID:4053028
2483830-13-1 suppliers list
Company Name: Reer Technology (Shanghai) Co., LTD  
Tel: 021-64400900 15800436310
Website: http://www.reertech.com/
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Website: www.caymanchem.com
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